Traditional varieties and wild pear from Serbia: A link among antioxidant, antidiabetic and cytotoxic activities of fruit peel and flesh

This study was aimed at evaluating the antioxidant and antidiabetic activities of methanolic extracts peel, flesh mixed flesh, as well cytotoxic activity peel obtained from fruits six traditional pear varieties (Vidovaca, Lubenicarka, Karamanka, Jeribasma, Loncara Takisa), one commercial variety (Williams Bartlett) a wild (Pyrus communis) Serbia. The tested showed strong regarding prevention ?-carotene bleaching high ?-glucosidase inhibition, no significant potential, with exception Williams Bartlett Pyrus communis extracts. Overall, most potent fruit part shown to be peel. active in all applied assays Takisa, while pear, P. communis, effective inhibiting proliferation cancer cells. In conclusion, several are promising candidates for further studies treatment pathological conditions associated effects oxidative stress, such diabetes even colorectal cancer.